Why the study?
Common analytical methods for monitoring cortisol levels cannot be used in real life due to bulky instruments and the need for specialized operators, which molecular probes can potentially solve.
Optical sensors and molecular probes offer a potential alternative to bulky analytical methods for real-time cortisol monitoring.
May enable portable cortisol monitoring for stress management; leaves open prospective clinical validation before adoption.
During a stress condition, the human body synthesizes catecholamine neurotransmitters and specific hormones (called "stress hormones"), the most important of which is cortisol. The monitoring of cortisol levels is extremely important for controlling the stress levels. For this reason, it has important medical applications. Common analytical methods (HPLC, GC-MS) cannot be used in real life due to the bulkiness of the instruments and the necessity of specialized operators. Molecular probes solve this problem. This review aims to provide a description of recent developments in this field, focusing on the analytical aspects and the possibility to obtain real practical devices from these molecular probes.
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Santonocito et al. (2023) studied this question.
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