March 1, 1988Acta Neurologica Scandinavica
Persistent hyperCKemia: fourteen patients studied in retrospect
Population
14 patients with persistently raised serum creatine kinase activity without established neuromuscular disorder
Design
Case_series
Authors
Discussion
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Member takes
Implication
Persistent hyperCKemia evaluation merits occupational and thyroid assessment; case reports leave open causality and generalizability.
Structured PICO
P
Population
14 patients with persistently raised serum creatine kinase activity (hyperCKemia) without established neuromuscular disorder
O
Outcome
Causes of persistent hyperCKemia
Persistent hyperCKemia without neuromuscular disease is often associated with manual labor, subclinical hypothyroidism, or myoadenylate deaminase deficiency, though some cases remain unexplained.
Cite This Study
Brewster et al. (1988) studied this question.