What question did this study set out to answer?

To evaluate the diversity and temporal stability of Haemophilus influenzae biotypes isolated from the respiratory tracts of individuals with cystic fibrosis.

June 1, 1988Journal of Medical Microbiology

Temporal changes in biotypes of Haemophilus influenzae isolated from patients with cystic fibrosis

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Authors

KWK. C. WatsonUniversity of KwaZulu-Natal EKE. J. C. KerrWestern General Hospital MBM. BaillieWestern General Hospital

Discussion

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Implication

Longitudinal study reveals rapid monthly shifts and diverse co-occurring biotypes of Haemophilus influenzae in cystic fibrosis, highlighting complex respiratory tract colonization.

Key Points

To evaluate the diversity and temporal stability of Haemophilus influenzae biotypes isolated from the respiratory tracts of individuals with cystic fibrosis.
Biotyped sequential respiratory isolates of Haemophilus influenzae collected over 2 years from 62 patients with cystic fibrosis.
Evaluated biotype diversity against a comparison group of 148 patients with non-cystic fibrosis respiratory infections.
Assessed the relationship between bacterial colony morphology and biotype classification.
Biotypes isolated from the respiratory tract showed rapid monthly turnover in cystic fibrosis, with only a small minority of patients maintaining a consistent biotype over several months.
Patients with cystic fibrosis harbored up to four biotypes simultaneously, whereas dual biotypes occurred in only one of 148 non-cystic fibrosis controls.
Colony morphology proved unreliable for biotyping, as identical biotypes displayed distinct colony forms and different biotypes exhibited identical appearances.

Cite This Study

Watson et al. (1988) studied this question.

synapsesocial.com/papers/6a7d43f3fac401f278425c4d https://doi.org/10.1099/00222615-26-2-129

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Implication

Longitudinal study reveals rapid monthly shifts and diverse co-occurring biotypes of Haemophilus influenzae in cystic fibrosis, highlighting complex respiratory tract colonization.

Temporal changes in biotypes of Haemophilus influenzae isolated from patients with cystic fibrosis

Discussion

Member takes

Implication

Key Points

Cite This Study

Temporal changes in biotypes of Haemophilus influenzae isolated from patients with cystic fibrosis

Discussion

Member takes

Implication

Key Points

Cite This Study

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