Why the study?
Does L-theanine prevent doxorubicin-induced nephrotoxicity in rats?
Population
32 male Sprague Dawley rats weighing 300-400 g
Comparison
L-theanine 200 mg/kg/day intraperitoneally for 5… vs Doxorubicin alone, L-theanine alone, and saline…
Design
Preclinical, randomly assigned
Follow-up
5 days
Authors
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May support L-theanine renoprotection in doxorubicin-treated rats; hypothesis-generating and requires clinical validation.
Does L-theanine prevent doxorubicin-induced nephrotoxicity in rats?
L-theanine may protect against doxorubicin-induced nephrotoxicity by enhancing the antioxidant system in a rat model.
Altınkaynak et al. (2018) studied this question.
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