Why the study?
Are Chinese patients who satisfy MADIT-II criteria at similar risk of sudden cardiac death as the original MADIT-II subjects?
Population
70 consecutive Chinese patients who satisfied MADIT-II criteria for ICD implantation but did not undergo ICD…
Comparison
No ICD implantation (observational cohort) vs Original published MADIT-II population
Design
Cohort
Follow-up
35 months
Authors
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SCD rates in Chinese MADIT-II patients match historical controls; extends generalizability but leaves open need for local RCTs.
Are Chinese patients who satisfy MADIT-II criteria at similar risk of sudden cardiac death as the original MADIT-II subjects?
Chinese patients meeting MADIT-II criteria have a similar risk of sudden cardiac death as the original MADIT-II cohort, supporting the appropriateness of ICD implantation in this population.
Siu et al. (2009) studied this question.
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