Supramolecular Modification of the Periphery of Dendrimers Resulting in Rigidity and Functionality

The construction of 32 scaffolds at the periphery of a fifth generation poly(propyleneimine) dendrimer, in which glycinylurea-modified molecules can be selectively bound, represents a novel approach to functionalize dendrimers (see schematic representation). These supramolecular architectures have enhanced rigidity and show reversibility of the modification.