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January 1, 2002Oncology

Acquired Resistance of Pancreatic Cancer Cells towards 5-Fluorouracil and Gemcitabine Is Associated with Altered Expression of Apoptosis-Regulating Genes

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Authors

XSXin ShiWuhan UniversitySLShengli LiuXinjiang Academy of Agricultural and Reclamation ScienceJKJörg KleeffRoche (Switzerland)

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Shi et al. (2002) studied this question.

synapsesocial.com/papers/6a7d4e78ade38b7dc346dc9chttps://doi.org/10.1159/000065068
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Activation of MAP kinases by 5-fluorouracil in a 5-fluorouracil-resistant variant human cell line derived from a KT breast cancer cell line.1998 · 13 citations
  2. 2Mechanisms for 5-Fluorouracil Resistance in Human Colon Cancer DLD-1 Cells.1998 · 21 citations
  3. 3Comparison between short or long exposure to 5-fluorouracil in human gastric and colon cancer cell lines: biochemical mechanism of resistance1998 · 31 citations
  4. 4Gemcitabine and Paclitaxel: Pharmacokinetic and Pharmacodynamic Interactions in Patients With Non–Small-Cell Lung Cancer1999 · 146 citations