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March 1, 1999Journal of Biological ChemistryOpen Access

The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene

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Authors

TSTatsuya SueyoshiTKTakeshi KawamotoIZIgor N. Zelko

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Cite This Study

Sueyoshi et al. (1999) studied this question.

synapsesocial.com/papers/6a7d540b3575152c8237de92https://doi.org/10.1074/jbc.274.10.6043
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.1998 · 1,582 citations
  2. 2Drug-Induced Changes in the Liver Endoplasmic Reticulum: Association with Drug-Metabolizing Enzymes1963 · 418 citations
  3. 3Characterization of a Phenobarbital-responsive Enhancer Module in Mouse P450 Cyp2b10 Gene1997 · 143 citations
  4. 4Olfaction in humans with special reference to odorous 16-androstenes: their occurrence, perception and possible social, psychological and sexual impact1993 · 177 citations
  5. 5Phenobarbital Alters Protein Binding to the CYP2B1/2Phenobarbital-responsive Unit in Native Chromatin1997 · 40 citations