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August 28, 2007Proceedings of the National Academy of SciencesOpen Access

Enhanced subunit interactions with gemcitabine-5′-diphosphate inhibit ribonucleotide reductases

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Authors

JWJun WangShanghai Jiao Tong UniversityGLGregory J. S. LohmanNew England Biolabs (United States)JSJoAnne StubbeHarvard University

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Wang et al. (2007) studied this question.

synapsesocial.com/papers/6a7d55cee6f633beba6e5702https://doi.org/10.1073/pnas.0706803104
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  1. 1A Comprehensive Model for the Allosteric Regulation of Mammalian Ribonucleotide Reductase. Functional Consequences of ATP- and dATP-Induced Oligomerization of the Large Subunit2001 · 96 citations
  2. 2Alternative model for mechanism-based inhibition of Escherichia coli ribonucleotide reductase by 2'-azido-2'-deoxyuridine 5'-diphosphate1993 · 57 citations
  3. 3Ribonucleotide Reductases2006 · 1,113 citations