Why the study?
Does intrapericardial instillation of mitoxantrone improve remission rates in patients with malignant pericardial effusion?
Population
16 patients with cytologically verified malignant pericardial effusions
Design
Case_series
Follow-up
mean 189 days
Authors
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May support intrapericardial mitoxantrone for malignant pericardial effusion palliation; hypothesis-generating case series leaves open need for randomized confirmation.
Does intrapericardial instillation of mitoxantrone improve remission rates in patients with malignant pericardial effusion?
Intrapericardial instillation of mitoxantrone is a highly effective and well-tolerated palliative therapy for malignant pericardial effusion, achieving a 94% response rate.
Musch et al. (2003) studied this question.
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