Why the study?
Does dexamethasone reduce postoperative nausea and vomiting compared to ondansetron in patients undergoing laparoscopic surgeries?
Population
592 patients from 7 RCTs undergoing laparoscopic surgeries
Comparison
Dexamethasone for prophylaxis of postoperative… vs Ondansetron
Design
Meta-analysis
Follow-up
24 hours
Authors
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Supports dexamethasone over ondansetron for early postoperative nausea in laparoscopic surgery; strengthens meta-analytic evidence for antiemetic selection.
Does dexamethasone reduce postoperative nausea and vomiting compared to ondansetron in patients undergoing laparoscopic surgeries?
Dexamethasone is superior to ondansetron in preventing postoperative nausea at 4-6 hours after laparoscopic surgery, though both are equally effective for vomiting up to 24 hours.
Maitra et al. (2016) studied this question.
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