Pulmonary arterial hypertension in congenital heart disease: translational opportunities to study the reversibility of pulmonary vascular disease
Population
Patients with pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD)
Design
Review
Authors
Discussion
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Implication
PAH-CHD cohorts may accelerate target discovery for vascular remodeling; leaves open validation of curative interventions in prospective trials.
Structured PICO
P
Population
Patients with pulmonary arterial hypertension associated with congenital heart disease (PAH-CHD)
PAH-CHD provides a unique clinical model to study the transition from reversible to irreversible pulmonary vascular disease, potentially identifying targets for curative pharmacological interventions.
Cite This Study
Feen et al. (2017) studied this question.