Unprecedentedly Fast DNA Hydrolysis by the Synergism of the Cerium(IV)-Praseodymium(III) and the Cerium(IV)-Neodymium(III) Combinations

The most active catalysts for DNA hydrolysis so far have been obtained by using the synergetic cooperation of the cerium(IV) ion with the praseodymium(III) ion. The pseudo first-order rate constant for the hydrolysis of thymidylyl(3′-5′)thymidine by the 2:1 combination is 10 times as great as that by the cerium(IV) ion.