Intramolecular attack of a hydroxyl group on a coordinated nitrile is the key step in the CoIII-catalyzed hydrolysis of nitriles to amides. The CoIII catalyst is highly selective; for example, the double bond of acrylonitrile remains intact during the hydrolysis.
No takes yet. Share an insight, caveat, or question.
Chin et al. (1990) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: