Primary hepatic lymphoma can mimic liver metastasis clinically and radiologically, requiring histopathology for definitive diagnosis.
Histopathology is required to distinguish PHL from metastasis; this case leaves open whether imaging algorithms can reliably exclude it.
A 59-year-old woman presented with the clinical symptoms and radiologic investigations of a liver lesion suspect of metastasis. However, postoperative histopathology revealed a primary hepatic lymphoma (PHL). The case of a patient with a solitary PHL, which was treated by resection and subsequent chemotherapy, will be discussed with a short overview of the literature.
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Ernst JA Steller (2012) studied this question.
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