Impact of Cardiac Implantable Electronic Device Infection
Why the study?
Current understanding of the impact of CIED infection is based on retrospective analyses from medical records or administrative claims data.
What are the clinical and economic impacts of major CIED infections in the US healthcare system?
Population
Patients with major CIED infections from the WRAP-IT trial
Comparison
Clinical and economic outcomes associated with major CIED infections
Design
Prespecified, as-treated analysis of trial data
Authors
Discussion
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Member takes
Implication
Major CIED infections drive prolonged therapy disruptions and high costs; leaves open optimal prevention strategies in real-world cohorts.
Structured PICO
What are the clinical and economic impacts of major CIED infections in the US healthcare system?
P
Population
Patients with major cardiac implantable electronic device (CIED) infections in the US healthcare system (from the WRAP-IT trial)
I
Intervention
Major CIED infection (observational exposure)
O
Outcome
Clinical and economic impacts including mortality, quality of life, disruption of CIED therapy, healthcare utilization, and costs
Major CIED infections severely impact patient quality of life and result in significant therapy disruptions and high healthcare costs in the US healthcare system.
Cite This Study
Wilkoff et al. (2020) studied this question.