What question did this study set out to answer?

October 25, 2010EP EuropaceOpen Access

Pulmonary vein ostium shape and orientation as possible predictors of occlusion in patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation

View Full Paper

Ask AI

Bookmark

Why the study?

Does pulmonary vein ostium shape and orientation evaluated by MSCT predict the degree of occlusion during cryoballoon ablation in patients with drug-refractory paroxysmal atrial fibrillation?

Key Points

To determine whether pulmonary vein ostium shape and orientation measured on pre-procedural multislice cardiac computed tomography predict balloon occlusion quality during cryoballoon ablation.
Retrospectively analyzed pre-procedural multislice cardiac computed tomography scans of 52 patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation.
Quantified pulmonary vein ostium ovality index and frontal-plane orientation for left and right pulmonary veins and correlated these parameters with intra-procedural catheter occlusion.
Pulmonary vein ostium orientation strongly correlated inversely with occlusion across all veins (LSPV: r = -0.804, P < 0.001; LIPV: r = -0.415, P = 0.013; RSPV: r = -0.798, P < 0.001; RIPV: r = -0.867, P < 0.001).
Left pulmonary vein ovality index demonstrated a significant inverse relationship with occlusion (LSPV: r = -0.486, P < 0.003; LIPV: r = -0.360, P = 0.033), whereas right pulmonary vein ovality was not significantly associated (RSPV: r = -0.283, P = 0.083; RIPV: r = 0.235, P = 0.093).

Structured PICO

Does pulmonary vein ostium shape and orientation evaluated by MSCT predict the degree of occlusion during cryoballoon ablation in patients with drug-refractory paroxysmal atrial fibrillation?

Population

52 patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation who had a pre-procedural multislice cardiac computed tomography (MSCT)

Intervention

Pre-procedural multislice cardiac computed tomography (MSCT) evaluation of pulmonary vein ostium shape (ovality) and orientation

Outcome

Degree of occlusion obtained during cryoballoon ablationsurrogate

Pre-procedural MSCT evaluation of pulmonary vein ostium shape and orientation can predict the degree of occlusion achievable during cryoballoon ablation for paroxysmal atrial fibrillation.

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

MSCT-derived PV orientation may aid cryoballoon planning; leaves open whether imaging improves outcomes in prospective trials.

Cite This Study

Chierchia et al. (2010) studied this question.

synapsesocial.com/papers/6a7d7306ade38b7dc346e58d https://doi.org/10.1093/europace/euq388

Topics

Persistent AF management Atrial fibrillation Echocardiography AF ablation outcomes

View Full Paper

Ask AI

Bookmark

Pulmonary vein ostium shape and orientation as possible predictors of occlusion in patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Topics

Pulmonary vein ostium shape and orientation as possible predictors of occlusion in patients with drug-refractory paroxysmal atrial fibrillation undergoing cryoballoon ablation

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider