What question did this study set out to answer?

To investigate the spectrum of Human herpesvirus 8 (HHV8) disease in liver transplant recipients and evaluate potential donor-derived infections.

August 13, 2026Transplant Infectious DiseaseOpen Access

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

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Implication

Case series and systematic review highlight varied HHV8 disease post-liver transplant, suggesting improved survival with targeted treatments and donor screening.

Key Points

To investigate the spectrum of Human herpesvirus 8 (HHV8) disease in liver transplant recipients and evaluate potential donor-derived infections.
Inclusion of 135 cases from literature and NSW data from 2017-2024
Comparison of disease manifestations by suspected donor-derived infection using statistical tests
Survival analysis using Cox proportional hazards model
33% of cases had suspected donor-derived infection
After 12 months of follow-up, 68 out of 125 experienced disease remission
Higher mortality observed in patients with visceral KS (aHR 5.83) and non-KS diseases (aHR 4.32), p = 0.002

Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6a7d75f62b0e0cff3f63ef1e https://doi.org/10.1111/tid.70293

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Implication

Case series and systematic review highlight varied HHV8 disease post-liver transplant, suggesting improved survival with targeted treatments and donor screening.

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Discussion

Member takes

Implication

Key Points

Cite This Study

Human Herpesvirus 8 Causes a Wide Spectrum of Disease in Liver Transplant Recipients and May be Donor Derived: Case Series and Systematic Review of an Emerging Challenge

Discussion

Member takes

Implication

Key Points

Cite This Study

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