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This study aims to describe the clinical and histopathological features of colorectal neoplasia in adults younger than 50 years.

Clinicopathological Characteristics of Colorectal Neoplasia in Adults Younger than 50 Years: A Real-World Single-Center Study

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This study aims to describe the clinical and histopathological features of colorectal neoplasia in adults younger than 50 years.
Retrospective single-center study including adults aged 18–49 years who underwent colonoscopy from January 2018 to December 2023.
Included 152 patients with colorectal lesions classified as benign, advanced, or malignant based on histopathological criteria.
Demographic, endoscopic, and pathological characteristics analyzed across lesion categories.
54.6% of patients had benign lesions, 42.1% had advanced neoplasia, and 3.3% had malignant lesions.
Advanced lesions predominantly observed in patients aged 40–49 years.
Larger lesion size significantly associated with advanced pathological features (p < 0.001).

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Retrospective study characterizes colorectal lesions in adults under 50 years, highlighting advanced neoplasia prevalence.

A 2026 study studied this question.

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