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August 13, 2026BMC MicrobiologyOpen Access

Risk factors and molecular epidemiology of ST2-type carbapenem-resistant Acinetobacter baumannii carrying blaOXA−23−like and blaOXA−51−like genes

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Authors

YXYong XiaXCXu ChenXSXue Wei Sun

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Overview

Randomized trial analyzes risk factors and molecular epidemiology of CRAB infections, highlighting implications for treatment strategies.

Key Points

  • This research aims to examine risk factors and molecular characteristics associated with carbapenem-resistant Acinetobacter baumannii infections.
  • Included 100 patients diagnosed with A. baumannii infection.
  • Performed univariate and multivariate analyses to identify risk factors for CRAB infection.
  • Conducted multilocus sequence typing and whole-genome sequencing on selected CRAB strains.
  • Length of hospital stay was significantly longer for CRAB patients (P=0.022, OR=1.068).
  • ICU admission rate was significantly higher in the CRAB group (P=0.019, OR=8.032).
  • 39 of 48 tested CRAB strains carried both bla OXA−23−like and bla OXA−51−like genes.

Cite This Study

Xia et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76312b0e0cff3f63f499https://doi.org/10.1186/s12866-026-05493-8
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