Differential effects of smoking status on serum bone biomarkers: a meta-analysis of case-control studies

Hossein Hassanpour

doi:10.17605/osf.io/52dsv

August 10, 2026Open Access

Differential effects of smoking status on serum bone biomarkers: a meta-analysis of case-control studies

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Key Points

This meta-analysis aims to evaluate the influence of smoking status on various serum bone biomarkers.
Conducted a systematic review and meta-analysis of case-control studies
Analyzed biomarkers including PTH, 25(OH)D, calcium, phosphate, osteocalcin, and BAP
Smoking is associated with altered levels of serum calcium and phosphate, although specific effect sizes were not provided.
A significant reduction in osteocalcin levels is observed in smokers, suggesting impaired bone metabolism.

Implication

Meta-analysis investigates smoking's impact on serum bone biomarkers, indicating potential health risks.

Abstract

This is a scientific manuscript reporting a systematic review and meta-analysis investigating how cigarette smoking affects serum bone biomarkers (PTH, 25(OH)D, calcium, phosphate, osteocalcin, and BAP).

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Cite This Study

Hossein Hassanpour (2026) studied this question.

synapsesocial.com/papers/6a7d76aa2b0e0cff3f640221 https://doi.org/10.17605/osf.io/52dsv

View Full Paper

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Differential effects of smoking status on serum bone biomarkers: a meta-analysis of case-control studies

Key Points

Implication

Abstract

Discussion

Cite This Study

Differential effects of smoking status on serum bone biomarkers: a meta-analysis of case-control studies

Key Points

Implication

Abstract

Discussion

Cite This Study

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