Demonstrates effective formation of sulfonyl ketones in allylic sulfones, suggesting a green synthetic method.
A metal-free, efficient, iodine(III)-promoted oxidative transformation of allylic sulfones/allylic triflones with water participation for accessing sulfonyl ketones and triflyl allylic alcohols is reported. This strategy enables the selective construction of two SO2-containing compounds with chemical and biological significance, and its success mainly relies on the substitution effect of the starting materials. Water serves as an eco-friendly oxygen atom source. This transformation has excellent selectivity, broad substrate scope, mild reaction conditions, and ease of scale-up.
No takes yet. Share an insight, caveat, or question.
Tong et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: