What question did this study set out to answer?

To highlight the occurrence of herpes simplex virus encephalitis in patients with acute brain injury or hemorrhage.

Herpes simplex virus encephalitis following acute brain injury: illustrative cases

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To highlight the occurrence of herpes simplex virus encephalitis in patients with acute brain injury or hemorrhage.
Presented three illustrative cases of HSVE following acute brain injury
Administered acyclovir treatment based on clinical suspicion
Utilized BioFire FilmArray Meningitis/Encephalitis Panel for diagnosis.
Two out of three patients died due to irreversible neurological damage and significant comorbidities
HSVE diagnosis is often overlooked due to initial brain injury symptoms
Prompt initiation of acyclovir therapy may mitigate outcomes.

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Illustrative cases reveal herpes simplex virus encephalitis in patients after acute brain trauma, suggesting vigilance warranted.

Shay et al. (2026) studied this question.

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