Review synthesizes challenges and strategies for implementing laboratory information systems integrated with EHRs in clinical settings, indicating practical solutions.
The laboratory information system (LIS) is an indispensable component of the modern clinical laboratory, underpinning day-to-day operations and playing a critical role in delivering quality patient care. Clinical laboratories are challenged to introduce new technologies within steady-state staffing, including navigating the complex process of implementing a new LIS. In recent years, a growing number of laboratories are transitioning to systems integrated within the EHR. The complexity increases further when LIS and EHR go live simultaneously, a scenario that is particularly challenging in integrated health systems. This review synthesizes the current literature as well as real-world experiences and lessons from the planning, build/validation, rollout readiness, stabilization, and optimization phases to offer practical strategies and operational insights for clinical laboratories undertaking LIS implementation, with particular attention to the unique considerations of concurrent EHR/LIS rollouts. Opportunities for future developments are also highlighted.
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Li Zha (2026) studied this question.
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