Why the study?
Myocarditis is common in children and can cause varying degrees of cardiac function damage, leading investigators to evaluate the effects of creatine phosphate treatment.
Does creatine phosphate improve myocardial function and enzyme profile in children with myocarditis?
Does creatine phosphate improve myocardial function and enzyme profile in children with myocarditis?
Creatine phosphate may be an effective and safe adjunctive treatment for improving cardiac function and myocardial enzyme profiles in pediatric myocarditis.
Answers are grounded in this paper and cite their sources.
Creatine phosphate was associated with better outcomes in pediatric myocarditis; leaves open need for RCTs before practice change.
Myocarditis in children is more common in clinical practice, which can cause different degrees of cardiac function damage. We investigated the effects of creatine phosphate in the treatment of myocarditis in children. Children in the control group were treated with sodium fructose diphosphate, and children in the observation group were treated with creatine phosphate on the basis of the control group. After treatment, the myocardial enzyme profile and cardiac function of children in the observation group were better than the control group. The total effective rate of treatment for children in the observation group was higher than that in the control group. In conclusion, creatine phosphate could significantly improve myocardial function, improve myocardial enzyme profile and reduce myocardial damage in children with pediatric myocarditis and had a high safety of use, which was worthy of clinical promotion.
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Lin et al. (2023) studied this question.
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