Key result
A 51-year-old female with primary cardiac lymphoma achieved a complete response to six cycles of R-CHOP chemoimmunotherapy, evidenced by the resolution of intracardiac masses.
Why the study?
Primary cardiac lymphoma comprises 1%-2% of primary cardiac tumors, and reports of rare presentations with rapid disease progression are limited.
Case Report (n=1)
Intra-cardiac echocardiography (ICE) can effectively guide endovascular biopsy for the diagnosis of primary cardiac lymphoma, enabling timely and successful treatment with R-CHOP chemoimmunotherapy.
Primary cardiac lymphoma (PCL) comprises of 1%-2% of primary cardiac tumors.This case report describes a rare case of PCL with rapid disease progression.A 51-year-old female presented with 6 months of dyspnea.Her transthoracic echocardiogram showed a large exudative circumferential pericardial effusion and bi-atrial masses.An endovascular tissue biopsy using intra-cardiac echocardiography guidance enabled the diagnosis of diffuse large B-cell lymphoma.Staging computed tomography staged the disease at Ann Arbor stage IV E.She achieved a complete response to rituximab, cyclophosphamide, hydroxydaunorubicin, vincristine, and prednisolone chemoimmunotherapy.
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Lim et al. (2023) conducted a case report in Primary cardiac lymphoma (n=1). R-CHOP chemoimmunotherapy was evaluated on Treatment response. A 51-year-old female with primary cardiac lymphoma achieved a complete response to six cycles of R-CHOP chemoimmunotherapy, evidenced by the resolution of intracardiac masses.
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