Key result
The most effective strategy for the prevention of stroke recurrence in young patients with patent foramen ovale remains uncertain, as high-level data have been lacking.
Why the study?
Does closure of the patent foramen ovale prevent stroke recurrence in young survivors of stroke?
Does closure of the patent foramen ovale prevent stroke recurrence in young survivors of stroke?
Highlights the ongoing uncertainty and lack of high-level evidence regarding the efficacy of PFO closure for preventing recurrent stroke in young patients.
In approximately 30% of young survivors of stroke, no clear cause is identified despite a thorough evaluation.1 Patent foramen ovale is found on transesophageal echocardiography in about half of these patients, as compared with approximately 25% of the general population. Clinicians, then, often assume that the patent foramen ovale was the cause of the stroke, although it may be incidental in some patients.24 The most effective strategy for the prevention of stroke recurrence in such patients is uncertain, and some experts recommend closure of the patent foramen ovale to prevent future embolic events, although high-level data have been lacking. . . .
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Messé et al. (2013) conducted an editorial in Stroke with patent foramen ovale. Patent foramen ovale closure was evaluated. The most effective strategy for the prevention of stroke recurrence in young patients with patent foramen ovale remains uncertain, as high-level data have been lacking.
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