Key result
Multidisciplinary treatment including surgical resection, chemotherapy, radiotherapy, and targeted therapy achieved an overall survival of 18 months in a pregnant patient with primary cardiac angiosarcoma.
Why the study?
Primary cardiac angiosarcoma is rare, highly invasive, and prone to metastasis, with surgical treatment being difficult and specific postoperative therapy regimens remaining controversial.
Does multidisciplinary treatment improve survival in a pregnant patient with primary cardiac angiosarcoma?
Population
1 patient with primary cardiac angiosarcoma at 19 weeks of pregnancy
Design
Case report and literature overview
Follow-up
18th month after surgery
Authors
Loading...
Hypothesis-generating for multidisciplinary therapy in pregnant cardiac angiosarcoma; prospective data needed to confirm survival benefit and fetal safety.
Case Report (n=1)
No
Does multidisciplinary treatment improve survival in a pregnant patient with primary cardiac angiosarcoma?
Multidisciplinary treatment including surgery, chemotherapy, and targeted therapy can prolong survival in patients with primary cardiac angiosarcoma, though cardiopulmonary bypass carries a high risk of fetal loss in pregnant patients.
Wang et al. (2025) conducted a case report in Primary cardiac angiosarcoma (n=1). Multidisciplinary treatment (surgery, radiotherapy, chemotherapy, targeted therapy) was evaluated on Overall survival. Multidisciplinary treatment including surgical resection, chemotherapy, radiotherapy, and targeted therapy achieved an overall survival of 18 months in a pregnant patient with primary cardiac angiosarcoma.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: