Key result
A 49-year-old woman with Klippel-Trenaunay-Weber syndrome developed soft tissue angiosarcoma of the breast, representing a previously unreported association.
Case Report (n=1)
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This case report highlights the first known association between Klippel-Trenaunay-Weber syndrome and the development of soft tissue angiosarcoma of the breast.
Angiosarcomas are neoplasms of blood or lymphatic vessels with aggressive behavior. We report the coexistence of this malignancy within soft tissue of the breast in a 49-year-old woman who was diagnosed with Klippel-Trenaunay-Weber syndrome (KTW-S) during childhood. The patient has no previous history of radiation therapy on the chest and does not have any known risk factor for developing angiosarcoma, except for her congenital disease. To the best of our knowledge, the association between soft tissue angiosarcoma of the breast and KTW-S has never been previously reported.
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Bugarín-Estrada et al. (2018) conducted a case report in Soft tissue angiosarcoma of the breast and Klippel-Trenaunay-Weber syndrome (n=1). Klippel-Trenaunay-Weber syndrome was evaluated on Development of soft tissue angiosarcoma of the breast. A 49-year-old woman with Klippel-Trenaunay-Weber syndrome developed soft tissue angiosarcoma of the breast, representing a previously unreported association.
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