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Reinforces multifactorial renin control; leaves open integrated modeling for hypertension and CKD management.
Renal renin release is affected by several systemic and intrarenal factors. Systemic factors include sympathetic nerves, circulating angiotensin II, blood pressure and salt balance of the organism. Intrarenal factors involved are nitric oxide and the prostaglandins, which stimulate renin secretion.
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Wagner et al. (1998) studied this question.
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