Key result
Heavy cannabis use was temporally associated with spontaneous coronary artery dissection in a 39-year-old woman, which resolved with conservative management at 6-month follow-up.
Why the study?
Spontaneous coronary artery dissection linked to cannabis exposure is rarely reported, and advanced intracoronary imaging is often limited in community hospital settings.
Case Report (n=1)
No
Answers are grounded in this paper and cite their sources.
This case highlights cannabis as a possible, under-recognized trigger for spontaneous coronary artery dissection (SCAD) and supports conservative management when high-risk features are absent.
This case report highlights a rare and diagnostically challenging presentation of spontaneous coronary artery dissection (SCAD) in a healthy 39-year-old woman, with symptoms beginning while smoking cannabis after heavy recent use. It also underscores real-world limitations in community settings where advanced intracoronary imaging may be unavailable or unsuitable and where diagnosis and management rely on angiographic morphology and clinical context. In our patient, angiography localized the culprit to the distal left circumflex (LCx) artery, with minimal atherosclerotic burden elsewhere. Extracoronary imaging was negative for fibromuscular dysplasia (FMD), and follow-up CT coronary angiography demonstrated interval healing features that strengthened diagnostic confidence compared with many prior published cannabis-related cases. The favorable outcome with conservative therapy aligns with contemporary recommendations for stable SCAD, supporting noninterventional strategies when high-risk features are absent. Overall, this report adds to the limited literature linking cannabis exposure to SCAD and highlights cannabis as a possible, under-recognized trigger warranting greater clinician awareness and further investigation.
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Bhanushali et al. (2026) conducted a case report in Spontaneous coronary artery dissection (SCAD) (n=1). Cannabis use was evaluated. Heavy cannabis use was temporally associated with spontaneous coronary artery dissection in a 39-year-old woman, which resolved with conservative management at 6-month follow-up.
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