What question did this study set out to answer?

To compare the microbial profiles and abundance of 40 bacterial taxa across supragingival and subgingival plaque in periodontally healthy individuals versus those with periodontitis.

September 1, 2000Journal Of Clinical Periodontology

Comparison of the microbiota of supra‐ and subgingival plaque in health and periodontitis

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Authors

LXLaurie‐Ann Ximenez‐FyvieUniversidad Nacional Autónoma de México AHAnne D. HaffajeeBoston University SSS. S. SocranskyBoston University

Discussion

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Implication

Cross-sectional analysis reveals elevated red complex pathogens and bacterial loads in periodontitis, indicating distinct microbial shifts across plaque niches.

Key Points

To compare the microbial profiles and abundance of 40 bacterial taxa across supragingival and subgingival plaque in periodontally healthy individuals versus those with periodontitis.
Cross-sectional study evaluating 22 periodontally healthy individuals (mean age 32±16 years) and 23 adults with periodontitis (mean age 51±14 years).
Collected 2,358 supragingival and subgingival plaque samples from the mesial aspect of teeth (excluding 3rd molars) and analyzed 40 bacterial taxa using whole genomic DNA probes and checkerboard DNA-DNA hybridization.
Assessed clinical parameters across 6 sites per tooth and evaluated group differences via the Mann-Whitney test with adjustment for multiple comparisons.
Total DNA probe counts (x10^5 ± SEM) were significantly elevated in periodontitis compared to healthy subjects for both supragingival plaque (132±17.5 vs. 72.1±11, p < 0.01) and subgingival plaque (100.3±18.4 vs. 22.1±6.6, p < 0.001).
Actinomyces species predominated across all groups, accounting for 63.2% of supragingival and 47.2% of subgingival plaque in healthy controls, compared to 48.0% and 37.8% in periodontitis patients.
Red complex species (Porphyromonas gingivalis, Bacteroides forsythus, and Treponema denticola) along with Prevotella, Fusobacterium, and Campylobacter species were significantly more prevalent and abundant subgingivally in periodontitis subjects.

Cite This Study

Ximenez‐Fyvie et al. (2000) studied this question.

synapsesocial.com/papers/6a7d95f8cf7e8b32dacb4c76 https://doi.org/10.1034/j.1600-051x.2000.027009648.x

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Implication

Cross-sectional analysis reveals elevated red complex pathogens and bacterial loads in periodontitis, indicating distinct microbial shifts across plaque niches.

Comparison of the microbiota of supra‐ and subgingival plaque in health and periodontitis

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparison of the microbiota of supra‐ and subgingival plaque in health and periodontitis

Discussion

Member takes

Implication

Key Points

Cite This Study

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