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November 19, 2015Circulation JournalOpen Access

The What, When, Who, Why, How and Where of Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA)

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Key result

Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a distinct clinical entity that requires systematic evaluation to identify and treat underlying causes such as coronary spasm, myocarditis, or plaque disruption.

Population

Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA)

Design

Review

Authors

SPSivabaskari PasupathyRTRosanna TavellaJBJohn F. Beltrame

Discussion

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Overview

Supports systematic MINOCA evaluation; leaves open optimal therapies for prospective trials.

Key Points

  • Synthesize the contemporary clinical understanding of myocardial infarction with non-obstructive coronary arteries (MINOCA), focusing on its diagnostic criteria, risk profiles, clinical relevance, and management.
  • Conducted a systematic narrative review evaluating current clinical evidence, diagnostic pathways, and management strategies for MINOCA.
  • Assessed diagnostic protocols and patient risk profiles identified during acute myocardial infarction evaluations utilizing coronary angiography.
  • Defines standardized diagnostic criteria and key clinical timeframes for suspecting MINOCA in acute heart attack presentations.
  • Identifies vulnerable patient demographics, evaluates mechanisms distinct from obstructive disease, and outlines targeted therapeutic pathways alongside priorities for future research.

Structured PICO

P
Population
Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA)

This review provides a comprehensive overview of the diagnostic criteria, risk factors, management, and future directions for myocardial infarction with non-obstructive coronary arteries (MINOCA).

Cite This Study

Pasupathy et al. (2015) conducted a review in Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA). Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a distinct clinical entity that requires systematic evaluation to identify and treat underlying causes such as coronary spasm, myocarditis, or plaque disruption.

synapsesocial.com/papers/6a7d96a429cd345315cda118https://doi.org/10.1253/circj.cj-15-1096
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Also Consider

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