Why the study?
Does acetylcholine infusion reveal endothelial dysfunction in angiographically normal coronary arteries in non-diabetic patients with acute myocardial infarction and one-vessel disease?
Population
20 non-diabetic patients with an acute myocardial infarction and one-vessel disease
Comparison
Serial acetylcholine doses (10 M, 10 M, 10 M and… vs Baseline measurements prior to infusion
Design
Cross-sectional
Authors
Loading...
Endothelial dysfunction may be prevalent in non-culprit arteries after MI; leaves open whether acetylcholine testing informs management.
Does acetylcholine infusion reveal endothelial dysfunction in angiographically normal coronary arteries in non-diabetic patients with acute myocardial infarction and one-vessel disease?
Endothelial dysfunction is present in the majority of angiographically normal, non-infarct related coronary arteries in patients with acute myocardial infarction and single-vessel disease.
Heras et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: