Serum levels of antibody to native DNA (nDNA) in patients with systemic lupus erythematosus (SLE) correlate with disease activity. We describe a sensitive, simple and rapid assay for these antibodies based on the observation that 3 H‐labeled nDNA passes through Millipore filters while 3 H‐nDNA complexed with specific antibody is retained. The simplicity and rapidity of this assay should allow general utilization of serum anti‐nDNA antibody determinations for monitoring disease activity in patients with SLE.
No takes yet. Share an insight, caveat, or question.
Ginsberg et al. (1973) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: