Synthesis, Characterization, Aggregation Behavior, Antifungal and Antibacterial Studies of a Novel Tetra-Metronidazole Substituted Zinc (II) Phthalocyanine

New metronidazole substituted phthalonitrile derivative was prepared by nucleophilic displacement reaction between metronidazole and 4-nitrophthalonitrile.Cyclotetramerization of this phthalonitrile derivative in the presence of zinc acetate gave the new tetrakis (3-(2-(2-methyl-5-nitroimidazol-1(1H)-yl) ethoxy)) phthalocyaninatozinc (II).The new component was purified and characterized via various spectroscopic methods including infrared IR, nuclear magnetic resonance 1H NMR, and UV-visible spectroscopy.The aggregation behavior of the new zinc (II) phthalocyanine was investigated in different solvents such as DMSO and DMF.Antimicrobial activity of this new macrocycle was tested against gram-negative bacteria, gram-positive bacteria, and different varieties of Candida.