2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS

Q: What is the clinical evidence from this study?

Population: Heart failure (implied by CRT-D use). Intervention: Multipoint Pacing (MPP) activation vs. Conventional CRT configuration. Primary outcome: Battery longevity.

Maria Grazia Bongiorni; Haran Burri; Jean‐Claude Deharo; Christoph Starck; Charles Kennergren; László Sághy; Archana Rao; Carlo Tascini; Nigel Lever; Andrzej Kutarski; Ignacio Fernández Lozano; Neil Strathmore; Roberto Costa; Laurence M. Epstein; Charles J. Love; Carina Blomström‐Lundqvist; Laurent Fauchier; Pascal Defaye; Davíð O. Arnar; Didier Klug; Serge Bovéda; Jens Cosedis Nielsen; Giuseppe Boriani; Shu Zhang; Andrew Martin; Jordan M. Prutkin; Claudio de Zuloaga

doi:10.1093/europace/euy050

Key Points

To establish standardized definitions, procedural endpoints, and data collection requirements for clinical trials and registries evaluating transvenous lead extraction in patients with cardiac implantable electronic devices.
An expert writing group commissioned by the European Heart Rhythm Association (EHRA) and endorsed by APHRS, HRS, and LAHRS reviewed existing evidence and data from the prospective ELECTRa registry (N=3555 across 19 countries).
The panel established formal criteria for extraction indications, technical approaches, procedural success categories, and complication reporting across percutaneous, hybrid, and surgical interventions.
Lead extraction was formally defined as the removal of a lead implanted for more than 1 year, or requiring specialized extraction equipment, or accessed via an alternative route to the implant vein.
Established precise classification schemes for device-related infections, venous stenosis, lead dysfunction, and major versus minor procedural complications categorized by intraprocedural, post-procedural (within 30 days), and late timeframes.
Outlined minimum data parameters and case report standards to address key knowledge gaps, including lead burden management, tool-specific efficacy, operator volume thresholds, and the utility of hybrid operating rooms.

PICO

P

Population

Heart failure (implied by CRT-D use)

I

Intervention / Comparator

Multipoint Pacing (MPP) activation vs Conventional CRT configuration

O

Primary Outcome

Battery longevity

Limitations

Little information regarding real-life battery longevity for the studied CRT-D device due to its recent commercialization.

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

This EHRA expert consensus statement standardizes definitions, endpoints, and data collection requirements to improve the quality and comparability of future clinical studies and registries on transvenous lead extraction.

Abstract

No abstract was published with this document — society guidelines, consensus pathways, and scientific statements are typically released without one. See the Key Points and the linked PDF for the full content.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Bongiorni et al. (2018) studied Heart failure (implied by CRT-D use). Multipoint Pacing (MPP) activation vs. Conventional CRT configuration was evaluated on Battery longevity.

synapsesocial.com/papers/6a7d9a510380f7c7805c9952 https://doi.org/10.1093/europace/euy050

View Full Paper

Ask AI

Bookmark

Share

2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS

Key Points

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

2018 EHRA expert consensus statement on lead extraction: recommendations on definitions, endpoints, research trial design, and data collection requirements for clinical scientific studies and registries: endorsed by APHRS/HRS/LAHRS

Key Points

PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading