Key result
Retinal photography noninvasively estimates relative changes in retinal blood flow and oxygen delivery.
Observational
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By photographic techniques measurements have been made in the human retina of vessel size, arteriovenous oxygen difference across the retina, and mean retinal circulation time. By combination of these methods estimates can be made of relative changes in retinal blood flow rate and in the rate of oxygen delivery from the retinal vascular system. Observations are presented on the response of the normal and diseased retinal circulation to a variety of stimuli, particularly changes in blood oxygen and carbon dioxide tensions.
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Hickam et al. (1966) conducted an observational in Normal and diseased retinal circulation. Photographic techniques and stimuli (changes in blood oxygen and carbon dioxide tensions) was evaluated on Retinal vessel size, arteriovenous oxygen difference, mean retinal circulation time, retinal blood flow rate, and rate of oxygen delivery. Photographic measurements of retinal vessel size, arteriovenous oxygen difference, and circulation time allow estimation of relative changes in retinal blood flow and oxygen delivery.
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