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January 1, 1979Annals of Internal Medicine

Electrophysiologic Evaluation of Elderly Patients with Sinus Bradycardia

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Why the study?

Does abnormal corrected sinus-node recovery time predict serious sinus node disease in elderly patients with persistent sinus bradycardia?

Population

103 elderly patients with persistent sinus bradycardia

Design

Cohort

Follow-up

mean 4.6 years

Authors

DGDietmar GannUniversity of Miami

Discussion

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Overview

May guide pacing decisions in syncope with sinus bradycardia; leaves open randomized validation of corrected sinus-node recovery time.

Key Points

  • To assess electrophysiologic characteristics, long-term survival, and the prognostic value of corrected sinus-node recovery time in patients with persistent sinus bradycardia.
  • Prospective evaluation and follow-up of N=103 patients with persistent sinus bradycardia over a mean duration of 4.6 years using electrophysiologic testing.
  • The 5-year survival rate was 74.8%, which was not significantly different from the 72% rate observed in the age- and sex-matched general population.
  • Abnormal corrected sinus-node recovery time demonstrated 66% sensitivity, with an overall predictive accuracy of 90% (37 of 41 patients) for serious sinus node disease and 100% (18 of 18 patients) in those presenting with syncope.

Structured PICO

Does abnormal corrected sinus-node recovery time predict serious sinus node disease in elderly patients with persistent sinus bradycardia?

P
Population
103 elderly patients with persistent sinus bradycardia
I
Intervention
Electrophysiologic evaluation measuring corrected sinus-node recovery time
O
Outcome
Accuracy of abnormal corrected sinus-node recovery time in predicting serious sinus node disease, and 5-year survival rate

Abnormal corrected sinus-node recovery time is a highly accurate predictor of serious sinus node disease in elderly patients with sinus bradycardia, particularly those with syncope, aiding in the selection of patients for pacemaker therapy.

Cite This Study

Dietmar Gann (1979) studied this question.

synapsesocial.com/papers/6a7da0dcac8a0219183c934fhttps://doi.org/10.7326/0003-4819-90-1-24
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Electrophysiologic evaluation of sinus node function in patients with sinus node dysfunction.1976 · 197 citations
  2. 2Sinus node recovery time in the elderly.1975 · 50 citations
  3. 3Clinical Value of Tests of Sino‐Atrial Function*1978 · 18 citations
  4. 4Significance of the Sinus-Node Recovery Time1972 · 461 citations
  5. 5Corrected sinus node recovery time. Experimental physiologic and pathologic determinants.1975 · 52 citations