Why the study?
What factors influence the susceptibility of newborn infants to infection with attenuated polioviruses?
Population
Over 1,000 newborn infants during the first 3 months of life
Design
Cohort
Authors
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Maternal antibody and feeding may affect newborn oral polio vaccine response; hypothesis-generating for tailored early immunization strategies.
What factors influence the susceptibility of newborn infants to infection with attenuated polioviruses?
Maternal antibody, breast feeding, and age significantly influence the susceptibility of newborn infants to oral attenuated poliovirus infection.
Warren et al. (1964) studied this question.
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