Why the study?
The long-term proportion and prognosis of healthy subjects with right precordial ST segment elevation without family history of sudden death were unclear.
Population
3,339 healthy subjects undergoing periodical medical examination from 1992 to 2001
Comparison
Subjects with coved or saddle-back type ST elevation vs those without such elevation
Design
Longitudinal cohort study with serial ECG follow-up
Follow-up
Median 4 years (IQR 4-8 years)
Authors
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Supports conservative management of incidental Brugada-like ECGs without family history; leaves open need for larger prospective studies on risk stratification.
Incidental Brugada-like ECG patterns in healthy individuals without a family history of sudden death are rare (1.22%) and associated with a very low risk of fatal arrhythmias.
Masao Sakabe (2003) studied this question.
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