Key result
Serum ferritin levels were significantly higher in dermatomyositis patients with acute/subacute interstitial pneumonia compared to those without (median 790 vs 186 ng/ml; P<0.0001).
Why the study?
Does serum ferritin predict the occurrence and prognosis of acute/subacute interstitial pneumonia in patients with dermatomyositis?
Population
64 patients with dermatomyositis, including 19 with acute/subacute interstitial pneumonia, 24 with chronic…
Comparison
Measurement of serum ferritin levels vs DM patients without A/SIP, and patients with…
Design
Cohort
Follow-up
6 months
Authors
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Serum ferritin was associated with acute/subacute interstitial pneumonia in dermatomyositis; leaves open its value for prediction or prognosis pending prospective validation.
Observational (n=64)
Does serum ferritin predict the occurrence and prognosis of acute/subacute interstitial pneumonia in patients with dermatomyositis?
Absolute Event Rate: 790% vs 186%
p-value: p=<0.0001
Serum ferritin is a strong predictor of the development and severity of acute/subacute interstitial pneumonia in patients with dermatomyositis, with levels ≥1500 ng/ml indicating poor prognosis.
Gono et al. (2010) conducted an observational in Dermatomyositis (n=64). Serum ferritin levels vs. Patients with dermatomyositis without acute/subacute interstitial pneumonia was evaluated on Serum ferritin levels (p=<0.0001). Serum ferritin levels were significantly higher in dermatomyositis patients with acute/subacute interstitial pneumonia compared to those without (median 790 vs 186 ng/ml; P<0.0001).
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