What question did this study set out to answer?

To evaluate the risk and incidence of malignant tumors in patients with rheumatoid arthritis compared to the general population.

January 1, 1995Scandinavian Journal of Rheumatology

The Risk of Cancer in Rheumatoid Patients in Japan

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To evaluate the risk and incidence of malignant tumors in patients with rheumatoid arthritis compared to the general population.
Follow-up cohort study of 655 eligible rheumatoid arthritis patients (131 males, 524 females) admitted between 1980 and 1989 at the Center for Adult Diseases in Osaka, Japan.
Patients were matched against the Osaka Cancer Registry database to track incident malignant tumors and compute observed-to-expected (O/E) incidence ratios.
A total of 26 patients (5 males, 21 females) developed cancer during the observation period.
Female rheumatoid arthritis patients had a significantly higher overall cancer incidence than the general population, with an O/E ratio of 1.71 (95% CI, 1.06–2.62).
Site-specific analyses in female patients demonstrated elevated risks for buccal cavity and pharynx cancers (O/E ratio = 12.93) and thyroid cancer (O/E ratio = 2.74).

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Implication

Cohort study reveals elevated overall and site-specific cancer risk in female rheumatoid arthritis patients, highlighting the need for targeted oncologic screening.

Cite This Study

Moritomo et al. (1995) studied this question.

synapsesocial.com/papers/6a7da338d491aa75eb1504fe https://doi.org/10.3109/03009749509099305

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Implication

Cohort study reveals elevated overall and site-specific cancer risk in female rheumatoid arthritis patients, highlighting the need for targeted oncologic screening.

The Risk of Cancer in Rheumatoid Patients in Japan

Key Points

Discussion

Implication

Cite This Study

The Risk of Cancer in Rheumatoid Patients in Japan

Key Points

Discussion

Implication

Cite This Study

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