Key result
Patients after repair of Tetralogy of Fallot had significantly higher plasma BNP levels than healthy controls (28.3 vs. 7.4 pg/mL, P=0.0001), correlating with right ventricular function parameters.
Population
54 children and adolescents, comprising 25 patients after repair of tetralogy of Fallot and 29 healthy…
Comparison
Tissue Doppler imaging and plasma B-type… vs Healthy children
Design
Case-control
Authors
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May aid non-invasive RV assessment in repaired TOF; leaves open prospective validation before clinical adoption.
Case-Control (n=54)
Absolute Event Rate: 28.3% vs 7.4%
p-value: p=0.0001
Tissue Doppler imaging parameters and BNP levels are significantly altered in patients with repaired tetralogy of Fallot and correlate with each other, suggesting their utility in non-invasively assessing right ventricular function.
Tokel et al. (2009) conducted a case-control in Tetralogy of Fallot (n=54). Tetralogy of Fallot repair vs. Healthy children was evaluated on Plasma BNP levels (p=0.0001). Patients after repair of Tetralogy of Fallot had significantly higher plasma BNP levels than healthy controls (28.3 vs. 7.4 pg/mL, P=0.0001), correlating with right ventricular function parameters.
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