Key result
Parechovirus encephalitis in older children can present with unique neurological symptoms such as hemidystonia or acute altered mental status, differing from typical neonatal presentations.
Why the study?
Parechovirus encephalitis is rarely reported in otherwise healthy pediatric populations outside of the neonatal period.
Case Report (n=2)
Human Parechovirus encephalitis, typically seen in neonates, can present with atypical neurological symptoms such as hemidystonia and altered mental status in older, otherwise healthy children.
Clinicians should consider parechovirus in older children with hemidystonia or altered mental status; case report extends phenotypic spectrum but remains hypothesis-generating.
Human Parechovirus encephalitis is an uncommon infection. Very few of the cases have been reported in the literature so far. These reports are mainly about neonatal encephalitis, primarily affecting preterm neonates. Parechovirus encephalitis in otherwise healthy pediatric populations is a rare entity. Here, we present two unique pediatric cases secondary to Parechovirus infection, one with hemidystonia and another with acute onset of altered mental status, confusion, and headache.
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Pandit et al. (2022) conducted a case report in Parechovirus encephalitis (n=2). Parechovirus infection was evaluated on Clinical presentation and MRI findings. Parechovirus encephalitis in older children can present with unique neurological symptoms such as hemidystonia or acute altered mental status, differing from typical neonatal presentations.
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