Key result
Autopsy confirmed the antenatal ultrasound diagnosis of hypoplastic left heart syndrome in two cases and added new findings, facilitating the understanding of the underlying pathology.
Case Report (n=2)
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Autopsy correlation with prenatal ultrasound in fetal HLHS confirms the diagnosis and provides additional pathological insights.
Hypoplastic left heart syndrome (HLHS) represents a spectrum of abnormalities which marks the underdevelopment of left side cardiac structures. We present the ultrasound and autopsy correlation of two cases with HLHS with core pathology as isolated mitral atresia in one and aortic atresia in another. In both the cases after diagnostic confirmation on ultrasound (US), the couple opted for termination of pregnancy and consented for autopsy. The correlation of US and autopsy images of HLHS, facilitated our understanding of pathology behind the image obtained on US. The autopsy not only confirmed the antenatal diagnosis, but also added new findings.
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Kumar et al. (2018) conducted a case report in Fetal hypoplastic left heart syndrome (n=2). Ultrasound and autopsy correlation was evaluated on Correlation of ultrasound and autopsy findings. Autopsy confirmed the antenatal ultrasound diagnosis of hypoplastic left heart syndrome in two cases and added new findings, facilitating the understanding of the underlying pathology.
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