Early Alzheimer's Disease

A 72-year-old man seeks consultation at the urging of his wife for increasing difficulty with memory over the past 2 years. Clients at his brokerage firm have expressed concern about his occasional lapses in memory. His wife reports that he frequently repeats questions about social appointments and becomes angry when she points this out. The physical examination is normal, but the patient has difficulty remembering elements of a brief story and difficulty in adding a small amount of change. Alzheimer's disease is suspected. How should this patient be evaluated and treated?