What question did this study set out to answer?

To differentiate patients with mild cognitive impairment (MCI) from healthy controls and those with very mild Alzheimer's disease (AD).

Mild Cognitive Impairment

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Clinical entity identified differentiates mild cognitive impairment from healthy controls and very mild AD, suggesting targeted treatments.

To differentiate patients with mild cognitive impairment (MCI) from healthy controls and those with very mild Alzheimer's disease (AD).
Characterization of MCI as a distinct clinical entity.
Comparison between MCI patients, healthy controls, and individuals with very mild AD.
Patients with MCI can be effectively differentiated from healthy controls.
MCI patients present distinct characteristics in comparison to those with very mild AD.

Petersen et al. (1999) studied this question.

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Clinical entity identified differentiates mild cognitive impairment from healthy controls and very mild AD, suggesting targeted treatments.