Key result
Protein kinase D-mediated signaling pathways play important roles in the cardiovascular system, particularly in the regulation of myocardial contraction, hypertrophy, and remodeling.
Design
Review
Authors
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May inform targeted therapies in hypertrophy and remodeling; leaves open clinical translation pending interventional studies.
This review highlights the emerging importance of protein kinase D signaling pathways in regulating myocardial contraction, hypertrophy, and remodeling.
Avkiran et al. (2008) conducted a review in Cardiovascular system regulation. Protein Kinase D (PKD) signaling was evaluated. Protein kinase D-mediated signaling pathways play important roles in the cardiovascular system, particularly in the regulation of myocardial contraction, hypertrophy, and remodeling.
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