Key result
Transcatheter aortic valve replacement via a direct transaortic approach in patients ineligible for transfemoral access demonstrated a 30-day mortality of 9.1% with no surgical conversions.
Why the study?
Is the transaortic approach for transcatheter aortic valve replacement safe and effective in patients with high surgical risk and inadequate transfemoral access?
Population
11 patients with aortic valve defects and high to very high operational risk, median age 75, 81.8% male, in…
Comparison
Transcatheter aortic valve replacement via… vs None in the Russian cohort. Transapical TAVR in…
Design
Cohort
Follow-up
30 days (Russian cohort); median 23 months (US abstract)
Authors
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Supports transaortic TAVR feasibility in high-risk patients ineligible for transfemoral access; leaves open need for randomized comparisons to other approaches.
Observational (n=11)
No
Is the transaortic approach for transcatheter aortic valve replacement safe and effective in patients with high surgical risk and inadequate transfemoral access?
The direct transaortic approach for TAVR is a safe and effective alternative for high-risk patients with inadequate transfemoral access.
Lardizabal et al. (2014) conducted an observational in Aortic valve defects (high surgical risk, ineligible for transfemoral approach) (n=11). Transaortic transcatheter aortic valve replacement was evaluated on 30-day mortality. Transcatheter aortic valve replacement via a direct transaortic approach in patients ineligible for transfemoral access demonstrated a 30-day mortality of 9.1% with no surgical conversions.
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